Evaluation of antidiarrheal effect of combination of Salam Leaves (Syzygiumpolyanthum) and Jackfruit Leaves (Artocarpus heterophyllus Lam.) infusum in rats induced by castor oil


 Backround: Diarrhoea is a condition characterised by watery, loose stools that occurs more than three times daily. In Indonesian traditional medicine, salam leaves and jackfruit have been used as herbal treatments for many conditions, including antidiarrheal medicines. Aims: The aim of this experimental study was to evaluate the effect combination Salam infusum induced castor oil in rats. Method: rats were divided into nine groups, where negative control group given CMC 1 %, positive tannins, five test groups with comparisons each dose administered orally. Castor stimulant diarrhoea. Results: results show all combinations leaves: effects decreased frequency defecation, faeces consistency, weight at ratios 1:1, 1:2, 1:3, 2:1, 3:1 compared (p < 0.05). Phytochemical indicated tannins. both infusums might be due presence which anti-secretory intestinal lumen. Conclusions: treatment has an effect. best result mixture infusum: ratio.